Endocrine Abstracts

Introduction & Objectives: A laparoscopic radical adrenalectomy is the standard treatment option for unilateral primary aldosteronism. Partial adrenalectomy for solitary adenomas has been suggested to be feasible and adrenal cortex-sparing. However, solitary adenomas may be rare. The purpose of this study was to assess whether partial adrenalectomy in patients with a seemingly solitary adenoma might be worthwhile by relating perioperative imaging to pathologic findings of ...

A 63-year-old woman was referred to our hospital for examination of three adrenal nodules. She had been diagnosed with hypertension since the age of 40 and prescribed antihypertensive drugs. Then, she was pointed out hypokalemia and bilateral adrenal tumors. She was diagnosed with primary aldosteronism (PA) at another hospital and had been prescribed spironolactone because the localization was not determined despite adrenal vein sampling (AVS) was performed.<p class="abste...

Background: Among patients diagnosed with primary aldosteronism (PA) due to an aldosterone producing adenoma (APA), about 10% fail to normalize aldosterone hypersecretion after unilateral adrenalectomy, and may instead have bilateral aldosterone producing hyperplasia. With routine histopathology it may be difficult to distinguish between APA and hyperplasia. We have recently reported the use of specific antibodies to identify the source of aldosterone excess in the removed adr...